Zocor (simvastatin) is a drug prescribed to reduce triglycerides, total cholesterol (LDL), and increasing HDL cholesterol. Common side effects of Zocor include diarrhea, vomiting, headache, and abdominal pain. Zocor belongs to the drug class of Statins. Uses and dosage information are provided. VYTORIN® (ezetimibe and simvastatin) Tablets. DESCRIPTION. VYTORIN contains ezetimibe, a selective inhibitor of intestinal cholesterol and related phytosterol absorption, and simvastatin, an HMG-CoA reductase inhibitor. This information has been updated in the December 15, 2011, FDA Drug Safety Communication: Revised dose limitation for Zocor (simvastatin) when taken with amiodarone. Zocor is the brand name of simvastatin, a prescription drug used to lower blood cholesterol. Zocor belongs to a class of drugs known as statins, also called HMG-CoA reductase inhibitors. Learn about Zocor (Simvastatin) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Vytorin is a combination of ezetimibe and simvastatin that is used for treating high levels of cholesterol in the blood. Vytorin reduces total cholesterol and low density lipoprotein (LDL or bad ) cholesterol while it increases high density lipoprotein (HDL or good ) cholesterol. Detailed Simvastatin dosage information for adults and children. Includes dosages for Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Heterozygous Familial Hypercholesterolemia and more; plus renal, liver and dialysis adjustments. Simvastatin (Zocor) is used to treat high cholesterol and to reduce risk of heart disease. Learn about its side effects, dosage, uses, and more. Simvastatin is an inexpensive drug used to lower levels of cholesterol and triglycerides in the blood. Simvastatin may also reduce the risk of heart attack or stroke in patients with risk factors for heart disease. Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or statins. It reduces levels of bad cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of good cholesterol (high-density lipoprotein, or HDL).